Dual monitor setup with two gpus.

I just installed macos sonoma 14.7 on my pc but my setup concludes an rx5500xt as my main gpu which is connected to my main monitor and a gtx 750 which is connected to a pretty horrible monitor due to the fact it only takes vga and the only thing i had lying around to be able to make this work was the gtx 750. my question is can i use both gpus so i can use both monitors on mac os or is that impossible cpu: 2600x gpu1:rx5500xt gpu2:gtx750