Change Video Card

Question: I've been running my Hackintosh for 3+ years. I've been perfectly content with it, BUT if I wanted/needed to change vidcards could I just plug and play it. I'm running:

High Sierra Clover GTX 960 i5 7400

I use it for audio production with Logic. I have my NVMe, and also a backup of it on a smaller ssd (original install disk)

Author: @T0xAvenja