USB-attached devices only work on specific ports even though they're detected

I've gone through the task of getting 11.2.3 installed on my configuration, building a USB map using Hackintool, and then using the resulting kext (removing USBInjectAll, etc.) to then update to 11.5.1. I can boot into the OS fine however I'm finding that devices connected to certain USB ports do not work even though they're detected according to Hackintool.

For example, I connect my keyboard to one port that was flagged as USB 3, 480 Mbps, they keyboard works fine. If I plug it into one...

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