May I edit DSDTs after upgrading GPU?

I recently finished an AMD build with Ryzen 9 b450. And a RX 590 from my last computer.

I want to put the RX 590 back in my older pc since it handles games well and I want the Ryzen workstation to be for 4K video editing.

The problem is that I’ll be able to get the new GPU in a couple weeks. I plan on getting an RX 5700XT.

Is it worth commencing with an open core installation or should I wait for the replacement GPU to arrive? if so are there other drivers/Kexts I must replace for the new GPU?

Thanks!